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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSF
All Species:
48.18
Human Site:
S577
Identified Species:
75.71
UniProt:
P46459
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46459
NP_006169.2
744
82594
S577
P
D
K
M
I
G
F
S
E
T
A
K
C
Q
A
Chimpanzee
Pan troglodytes
XP_511626
842
92301
S650
P
D
K
M
I
G
F
S
E
T
A
K
C
Q
A
Rhesus Macaque
Macaca mulatta
XP_001105450
854
93325
S687
P
D
K
M
I
G
F
S
E
T
A
K
C
Q
A
Dog
Lupus familis
XP_548044
752
83541
S577
P
D
K
M
I
G
F
S
E
T
A
K
C
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P46460
744
82595
S577
P
D
K
M
I
G
F
S
E
T
A
K
C
Q
A
Rat
Rattus norvegicus
Q9QUL6
744
82634
S577
P
D
K
M
I
G
F
S
E
T
A
K
C
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418094
740
82158
S577
P
D
K
M
I
G
F
S
E
T
A
K
C
Q
A
Frog
Xenopus laevis
P23787
805
89193
W551
G
P
E
L
L
T
M
W
F
G
E
S
E
A
N
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
W551
G
P
E
L
L
T
M
W
F
G
E
S
E
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46461
745
82537
T577
P
E
D
M
V
G
Y
T
E
S
A
K
C
L
H
Honey Bee
Apis mellifera
XP_001120201
743
82591
T580
P
E
D
M
V
G
F
T
E
S
A
K
C
L
S
Nematode Worm
Caenorhab. elegans
Q94392
824
91316
S654
P
E
D
T
V
G
F
S
E
S
A
K
C
M
A
Sea Urchin
Strong. purpuratus
NP_999752
746
82671
S581
A
E
D
M
V
G
F
S
E
S
A
K
C
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0Y8
742
81469
S571
A
E
T
M
I
G
L
S
E
S
T
K
C
A
H
Baker's Yeast
Sacchar. cerevisiae
P18759
758
84038
S598
P
N
E
L
S
G
M
S
E
S
A
K
I
A
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
86.8
98.1
N.A.
98.1
97.8
N.A.
N.A.
93.6
26.2
25
N.A.
62.4
65.8
50.6
64.8
Protein Similarity:
100
88.2
87.1
98.8
N.A.
99.7
99.7
N.A.
N.A.
96.5
44.2
44.4
N.A.
77.7
81.1
66.2
80.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
0
0
N.A.
46.6
53.3
60
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
20
20
N.A.
80
86.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.6
64.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
0
0
0
0
0
80
0
0
27
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% C
% Asp:
0
47
27
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
34
20
0
0
0
0
0
87
0
14
0
14
0
0
% E
% Phe:
0
0
0
0
0
0
67
0
14
0
0
0
0
0
0
% F
% Gly:
14
0
0
0
0
87
0
0
0
14
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% H
% Ile:
0
0
0
0
54
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
47
0
0
0
0
0
0
0
0
87
0
0
0
% K
% Leu:
0
0
0
20
14
0
7
0
0
0
0
0
0
14
0
% L
% Met:
0
0
0
74
0
0
20
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
14
% N
% Pro:
74
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
0
0
74
0
40
0
14
0
0
7
% S
% Thr:
0
0
7
7
0
14
0
14
0
47
7
0
0
0
0
% T
% Val:
0
0
0
0
27
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _